France, 1939. At the dawn of World War II, Anne Guichard, a young archivist is employed at the Louvre. Once they reach Paris, the Nazis will stop at nothing to get their hands on the Louvre's art collection. With the Germans hard on their heels, Anne frantically moves the Mona Lisa and other treasures again and again in an elaborate game of hide and seek. Florence, 1479. House servant Bellina Sardi's future seems fixed when she accompanies her newly married mistress, Lisa Gherardini, to her home across the Arno. But soon, Bellina finds herself bewitched by a charismatic monk who has urged Florentines to rise up against the Medici family. When Master Leonardo da Vinci is commissioned to paint a portrait of Lisa, Bellina finds herself tasked with hiding an impossible secret.